产品货号：
Z29578
中文名称：
VISTA/VSIR抗体
英文名称：
Anti-VISTA/VSIR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-VISTA/VSIR Antibody |
| 指标别名 | B7-H5;C10orf54;GI24;Platelet receptor Gi24;PP2135;SISP1;UNQ730/PRO1412;VISTA |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,ICC,IF |
| 基因名称 | VSIR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | VISTA antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human VISTA.The immunogen is located within the last 60 amino acids of VISTA. |
| 计算分子量 | 34kDa |
| 成分 | VISTA Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | VISTA Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1),negatively regulating T-cell function and homeostasis (2).It is expressed in B,T,and NK cells,monocytes,and dendritic cells (3),and acts to regulate T cell expansion (4).LAG3 is also an important immune checkpoint protein,with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions.Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1,suggesting that a dual antibody approach may prove useful in cancer immunotherapy (5). |
| Uniprot ID | Q9H7M9 |
| 基因名全称 | VISTA molecule |
| 蛋白名全称 | VISTA molecule |
| 推荐稀释比 | VISTA antibody can be used for Immunohistochemistry at 2μg/mL.For Immunoflorescence start at 20μg/mL.For Immunocytochemistry start at 1μg/mL.Antibody validated:Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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